Delivering Science Supporting Healthcare

Cholesterol

Service
Test Background

The fasting lipid profile assesses total cholesterol and total triglycerides, in addition to the high and low density lipoprotein cholesterol fractions, from which ratios may be derived.

A patient's lipid status is an independent modifier of cardiovascular disease pathology. Its subsequent targeting, by pharmacological or dietary means, lowers the risk for developing such diseases.

Clinical Indications

Family history of cardiovascular or other thrombotic events
Diagnosis and monitoring of hyperlipidaemia
Monitoring of high-risk groups, eg. hypertensive, obese, diabetics, etc.

Reference Range

See notes below

Sample volume
0.5 mL
Turnaround time
1 day
Sample & Container Required
SST (gold top)
Notes

In primary prevention, lipid results should be assessed in tandem with other risk factors to estimate cardiovascular disease (CVD) risk. NICE recommend using the QRISK2 calculator In primary prevention, lipid results should be assessed in tandem with other risk factors to estimate cardiovascular disease (CVD) risk. NICE recommend using the QRISK2 calculator

https://www.qrisk.org/2017/

When considering treatment for primary prevention of CVD in individuals with ≥10% risk, share the option to have treatment or not before prescribing.

Patient decision aids include:

http://www.jbs3risk.com/JBS3Risk.swf

https://www.nice.org.uk/guidance/cg181/resources/patient-decision-aidpdf-243780159

Non-HDL cholesterol (total chol minus HDL chol) is recommended for CVD risk prediction; fasting samples are not required for this. Non-HDL cholesterol targets for patients treated for CVD risk reduction are:

* 40 % reduction from baseline (NICE CG181, 2014) or

* <2.5 mmol/L (JBS3. Heart 2014;100:ii1)

Once a patient has reached their target level of cholesterol, there is no need to keep measuring it.

Record last updated
August 15, 2025

Sample Container

5ml SST Vacutainers (Gold / Yellow top)

Search test database

Test Results

Yes, we have a Pathology User Guide

Yes. Please email your request to Imperial.nwlpcustomerservice@nhs.net

Results are communicated to clinical staff and are normally not communicated direct to patients either on telephone requests or in written report. If you need to contact us please click here to view the contact details page

Please contact the Customer Service Team Monday to Friday from 8:30am – 6:00pm on 0203 313 5353. Alternatively, see the Pathology User Guide for how to contact the relevant department. If advice is not urgent you can also email your query to Imperial.nwlpcustomerservice@nhs.net

Additional tests may be added by discussion with the relevant laboratory. The time limit for adding additional tests to a sample already received in the laboratory will depend on the type of sample and the department it was sent to.

Information on the repertoire of tests performed by pathology, including reference ranges, turnaround times and specimen requirements, can be found in the test directory.

NWLP operates UKAS accredited medical laboratories as per the references below. The current scope of accreditation for all NWLP’s laboratories can be found on the UKAS website.

See the following UKAS ref numbers:

  • Clinical Biochemistry Ref: 8673
  • Haematology and Blood Transfusion Ref: 8674
  • Infection & Immunity Sciences (Including Immunology, Virology, Microbiology and Histocompatibility and Immunogenetics ) Ref: 8659
  • Cellular Pathology (Including Histopathology, Cytology and Molecular Pathology) Ref: 9615

If you require copies of our certificate of accreditation and associated documentation please contact Imperial.nwlpcustomerservice@nhs.net.

UKAS requires the laboratories to be accredited for a particular repertoire/scope (ISO15189), any changes or additions to repertoire require assessment by UKAS (extension to scope).

The BD Hospital Tube GuideBD GP Tube Guide and BD Paediatric Tube Guide provide visual references to the correct tube types and collection instructions.

Home testing

INSTRUCTION SHEET FOR BLOOD SAMPLE COLLECTION 

We also have two instruction videos available (one with subtitles and one without) – please click on the links to view the videos on Google.

VIDEO ON BLOOD SAMPLE COLLECTION (without subtitles)

VIDEO ON BLOOD SAMPLE COLLECTION (with subtitles)

Our accreditations

Upholding excellence in diagnostic standards

Our laboratories are accredited by the UK Accreditation Service (UKAS) against the international standard ISO15189:2022. UKAS is the accreditation body for the UK that assesses medical laboratories.

Find out more about our accreditations on the UKAS website.

UKAS website
Man in the lab handling a sample