Delivering Science Supporting Healthcare

Growth hormone (GH)

Test Background

GH is a peptide hormone that stimulates growth and cell reproduction. It directly stimulates division and multiplication of chondrocytes of the cartilage and mediates production of insulin-like growth factor-1 (IGF-1). Its influences are widespread and include: increasing bone mineralisation, expanding muscle mass, promoting lipolysis and protein synthesis, stimulating organ growth (excluding the brain) and encouraging hepatic gluconeogenesis.
GH excess typically reflects the presence of pituitary adenoma and deficiency: a genetic disorder (such as Laron syndrome), congenital malformation or paradoxically pituitary tumour.

Clinical Indications

Excess: presentation of acromegaly in adults; thickening of the jaws and extremities with or without insulin resistance, carpal tunnel syndrome, muscle weakness and lethargy
Suspected primary gigantism in children
Deficiency: growth retardation in children/delayed sexual maturity. In adults, truncal obesity, decreased relative muscle mass and lethargy

Reference Range

Excludes acromegaly: 6 μg/L GH suppression test 60-120 minutes after glucose: 4.2 or 6 μg/L (DFT dependent)

Sample volume
0.5 mL
Turnaround time
1 week
Sample & Container Required
Serum (red top) or SST (gold top) (fasting, 30 mins rest preferred, random sample accepted)
Transport Storage
Stable at 2-8°C for 24 hours. Please freeze pending dispatch for analysis. Send to lab frozen.
Notes

Grossly haemolysed samples are unsuitable for this assay.

Record last updated
August 20, 2025

Sample Container

6ml Plain Vacutainers (Red top)

Sample Container

5ml SST Vacutainers (Gold / Yellow top)

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Test Results

Yes, we have a Pathology User Guide

Yes. Please email your request to Imperial.nwlpcustomerservice@nhs.net

Results are communicated to clinical staff and are normally not communicated direct to patients either on telephone requests or in written report. If you need to contact us please click here to view the contact details page

Please contact the Customer Service Team Monday to Friday from 8:30am – 6:00pm on 0203 313 5353. Alternatively, see the Pathology User Guide for how to contact the relevant department. If advice is not urgent you can also email your query to Imperial.nwlpcustomerservice@nhs.net

Additional tests may be added by discussion with the relevant laboratory. The time limit for adding additional tests to a sample already received in the laboratory will depend on the type of sample and the department it was sent to.

Information on the repertoire of tests performed by pathology, including reference ranges, turnaround times and specimen requirements, can be found in the test directory.

Different tests have different sample stability requirements. If a comment on results indicates that the sample was delayed, the links below will indicate which tests may have been affected. This information is for serum or plasma samples.

For some tests, the impact of delay is consistent and these are marked with an arrow:

↑ indicates tests where delayed centrifugation results in falsely elevated results and the true level is likely lower than that reported.

↓ indicates tests where delayed centrifugation results in falsely lowered results and the true level is likely higher than that reported.

If there is no arrow, the true level may be lower or higher than reported.

Please interpret results with caution and consider the impact of any uncertainty.

The comment on the report will state how delayed the sample was. Please click the relevant link  below to see which other tests may have been affected.

>8h >12h >24h >48h >72h

NWLP operates UKAS accredited medical laboratories as per the references below. The current scope of accreditation for all NWLP’s laboratories can be found on the UKAS website.

UKAS accredited medical laboratory/medical diagnostic service:

  • Clinical Biochemistry No. 8673
  • Haematology and Blood Transfusion No. 8674
  • Infection & Immunity Sciences (Including Immunology, Virology, Microbiology and Histocompatibility and Immunogenetics ) No. 8659
  • Cellular Pathology (Including Histopathology, Cytology and Molecular Pathology) No. 9615

If you require copies of our certificate of accreditation and associated documentation please contact Imperial.nwlpcustomerservice@nhs.net.

UKAS requires the laboratories to be accredited for a particular repertoire/scope (ISO15189), any changes or additions to repertoire require assessment by UKAS (extension to scope).

The BD Hospital Tube GuideBD GP Tube Guide and BD Paediatric Tube Guide provide visual references to the correct tube types and collection instructions.

Home testing

INSTRUCTION SHEET FOR BLOOD SAMPLE COLLECTION 

We also have two instruction videos available (one with subtitles and one without) – please click on the links to view the videos on Google.

VIDEO ON BLOOD SAMPLE COLLECTION (without subtitles)

VIDEO ON BLOOD SAMPLE COLLECTION (with subtitles)

Our accreditations

Upholding excellence in diagnostic standards

Our laboratories are accredited by the UK Accreditation Service (UKAS) against the international standard ISO15189:2022. UKAS is the accreditation body for the UK that assesses medical laboratories.

Find out more about our accreditations on the UKAS website.

UKAS website
Man in the lab handling a sample