Delivering Science Supporting Healthcare

Histopathology

Service
Clinical Indications

Microscopic information about the behaviour and nature of cells within a tissue sample is examined in order to supplement and guide the clinical team to develop the most appropriate treatment pathway for each individual patient.

Turnaround time
(Excluding cases requiring decalcification, referral or other additional investigations) the department aims to have 80% reported within 7 calendar days and 90% reported within 10 calendar days. Due to the complex interpretive nature of histopathology specimens this may not always be achievable.

Our current performance is 77%.

On all sites, urgent specimens must be received by 12:00 for same day results. For rapid renal biopsies, specimens must be received by 13:30.

Sample & Container Required
Whole unprocessed tissue samples – a sample of tissue or an organ needs to be sent to the Histopathology department in an adequately sized container, fully labelled with patient demographics and sample type (eg. duodenal biopsy). All whole unprocessed tissue samples require sufficient 10 % formal saline/10 % neutral buffered formalin to cover the specimen
Unstained sections on glass slides – as many slides as deemed appropriate on adhesive slides, fully labelled with the patient demographics in a sealed slide carrier
Wax blocks – as many blocks as deemed appropriate, marked with the sending laboratory’s accession number. Wrap the blocks in protective material to prevent crushing damage in transit
Notes

At times, it may be necessary to refer work to other laboratories or consultants. This requirement is assessed on a case-by-case basis. Referral centres are selected based on the EQA schemes in which they participate, any reported EQA exceptions, average turnaround times and accreditation status.

There are occasions where a centre without accreditation status is used; this is because it is a national referral centre and, on this basis, is deemed expert in this field. When cases require a specialist second opinion, they are referred by our pathologist to another pathologist, in line with the West London Cancer Network guidelines.

Hillingdon Hospital Mohs micrographic surgery – the laboratory is not UKAS accredited for this test for this sample type.

Muscle Biopsy specimens – the laboratory is not UKAS accredited for this test for this sample type.

Referral cases

Unless otherwise specified, the macroscopic description for all outsourced reports is completed internally. The name of the reporting pathologist name is included within the Final Diagnosis of the report and the referring centre is located on the report footer. The report and the referring centres used for primary report generation are as follows:

– Royal National Orthopaedic Hospital
– Source Bioscience

For cases referred to UCL Queen Square Institute of Neurology, the full report is provided by the referring hospital, and the referral case is stated in the macroscopic description.

Record last updated
August 21, 2025

Sample Container

60ml Universal container - Sputum and Fluids (White top)

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Test Results

Yes, we have a Pathology User Guide

Yes. Please email your request to Imperial.nwlpcustomerservice@nhs.net

Results are communicated to clinical staff and are normally not communicated direct to patients either on telephone requests or in written report. If you need to contact us please click here to view the contact details page

Please contact the Customer Service Team Monday to Friday from 8:30am – 6:00pm on 0203 313 5353. Alternatively, see the Pathology User Guide for how to contact the relevant department. If advice is not urgent you can also email your query to Imperial.nwlpcustomerservice@nhs.net

Additional tests may be added by discussion with the relevant laboratory. The time limit for adding additional tests to a sample already received in the laboratory will depend on the type of sample and the department it was sent to.

Information on the repertoire of tests performed by pathology, including reference ranges, turnaround times and specimen requirements, can be found in the test directory.

NWLP operates UKAS accredited medical laboratories as per the references below. The current scope of accreditation for all NWLP’s laboratories can be found on the UKAS website.

See the following UKAS ref numbers:

  • Clinical Biochemistry Ref: 8673
  • Haematology and Blood Transfusion Ref: 8674
  • Infection & Immunity Sciences (Including Immunology, Virology, Microbiology and Histocompatibility and Immunogenetics ) Ref: 8659
  • Cellular Pathology (Including Histopathology, Cytology and Molecular Pathology) Ref: 9615

If you require copies of our certificate of accreditation and associated documentation please contact Imperial.nwlpcustomerservice@nhs.net.

UKAS requires the laboratories to be accredited for a particular repertoire/scope (ISO15189), any changes or additions to repertoire require assessment by UKAS (extension to scope).

The BD Hospital Tube GuideBD GP Tube Guide and BD Paediatric Tube Guide provide visual references to the correct tube types and collection instructions.

Home testing

INSTRUCTION SHEET FOR BLOOD SAMPLE COLLECTION 

We also have two instruction videos available (one with subtitles and one without) – please click on the links to view the videos on Google.

VIDEO ON BLOOD SAMPLE COLLECTION (without subtitles)

VIDEO ON BLOOD SAMPLE COLLECTION (with subtitles)

Our accreditations

Upholding excellence in diagnostic standards

Our laboratories are accredited by the UK Accreditation Service (UKAS) against the international standard ISO15189:2022. UKAS is the accreditation body for the UK that assesses medical laboratories.

Find out more about our accreditations on the UKAS website.

UKAS website
Man in the lab handling a sample