Delivering Science Supporting Healthcare

Lead (Pb)

Test Background

Trace elements can be essential or toxic. Trace element toxicity can occur as a result of occupational exposure, environmental exposure or iatrogenic toxicity. Any organ can be affected: the central nervous system, liver, kidneys, muscles or circulatory system. All elements can be toxic in excess. Those most commonly associated with toxicity include: aluminium, lead, arsenic, cadmium, mercury and thallium.

Lead is a non-essential element and toxic effects occur through its accumulation in the body, reflecting its extensive use in silver smelting, paint production, jewellery making, building construction, petrol use and its ubiquitous presence in the water supply. Acute poisoning is now uncommon, however, chronic poisoning may often be due to industrial exposure, ingestion of lead-containing paint/contaminated dirt in children, or ingestion of contaminated alternative herbal therapy.

Clinical Indications

Symptoms include abdominal pain, fatigue, weakness, anaemia, basophilic stippling of erythrocytes and peripheral neuropathy.

Reference Range

Blood
<0.24 µmol/L

Urine
<13.7 nmol/L
<3.4 nmol/mmol creatinine
<39.5 nmol/24hr

Sample volume
0.5 mL
Turnaround time
2 weeks
Sample & Container Required
Whole Blood: EDTA Trace element tube (Royal blue cap), EDTA (lavender top) or heparin (green top). Urine: sterile universal or plain 24 hr collection
Transport Storage
Stable at 2-8°C. Sample can be sent by first class post.

Record last updated
September 5, 2025

Sample Container

6ml Trace Metal Silica (Navy blue top with purple band on label)

Sample Container

4ml EDTA Vacutainers (Lavender top)

Sample Container

6ml Lithium Heparin (Green top)

Sample Container

150ml Universal Container for Urine TB (Silver top)

Sample Container

24hr Urine Bottle (Plain label)

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Test Results

Yes, we have a Pathology User Guide

Yes. Please email your request to Imperial.nwlpcustomerservice@nhs.net

Results are communicated to clinical staff and are normally not communicated direct to patients either on telephone requests or in written report. If you need to contact us please click here to view the contact details page

Please contact the Customer Service Team Monday to Friday from 8:30am – 6:00pm on 0203 313 5353. Alternatively, see the Pathology User Guide for how to contact the relevant department. If advice is not urgent you can also email your query to Imperial.nwlpcustomerservice@nhs.net

Additional tests may be added by discussion with the relevant laboratory. The time limit for adding additional tests to a sample already received in the laboratory will depend on the type of sample and the department it was sent to.

Information on the repertoire of tests performed by pathology, including reference ranges, turnaround times and specimen requirements, can be found in the test directory.

Different tests have different sample stability requirements. If a comment on results indicates that the sample was delayed, the links below will indicate which tests may have been affected. This information is for serum or plasma samples.

For some tests, the impact of delay is consistent and these are marked with an arrow:

↑ indicates tests where delayed centrifugation results in falsely elevated results and the true level is likely lower than that reported.

↓ indicates tests where delayed centrifugation results in falsely lowered results and the true level is likely higher than that reported.

If there is no arrow, the true level may be lower or higher than reported.

Please interpret results with caution and consider the impact of any uncertainty.

The comment on the report will state how delayed the sample was. Please click the relevant link  below to see which other tests may have been affected.

>8h >12h >24h >48h >72h

NWLP operates UKAS accredited medical laboratories as per the references below. The current scope of accreditation for all NWLP’s laboratories can be found on the UKAS website.

UKAS accredited medical laboratory/medical diagnostic service:

  • Clinical Biochemistry No. 8673
  • Haematology and Blood Transfusion No. 8674
  • Infection & Immunity Sciences (Including Immunology, Virology, Microbiology and Histocompatibility and Immunogenetics ) No. 8659
  • Cellular Pathology (Including Histopathology, Cytology and Molecular Pathology) No. 9615

If you require copies of our certificate of accreditation and associated documentation please contact Imperial.nwlpcustomerservice@nhs.net.

UKAS requires the laboratories to be accredited for a particular repertoire/scope (ISO15189), any changes or additions to repertoire require assessment by UKAS (extension to scope).

The BD Hospital Tube GuideBD GP Tube Guide and BD Paediatric Tube Guide provide visual references to the correct tube types and collection instructions.

Home testing

INSTRUCTION SHEET FOR BLOOD SAMPLE COLLECTION 

We also have two instruction videos available (one with subtitles and one without) – please click on the links to view the videos on Google.

VIDEO ON BLOOD SAMPLE COLLECTION (without subtitles)

VIDEO ON BLOOD SAMPLE COLLECTION (with subtitles)

Our accreditations

Upholding excellence in diagnostic standards

Our laboratories are accredited by the UK Accreditation Service (UKAS) against the international standard ISO15189:2022. UKAS is the accreditation body for the UK that assesses medical laboratories.

Find out more about our accreditations on the UKAS website.

UKAS website
Man in the lab handling a sample