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Zinc (Zinc, TPN, Acrodermatitis, Enteropathica)

Test Background

Zinc is an essential trace element, stored mainly in muscle. Approximately 80 % of circulating zinc is present in the red cells. Zinc is a component of many enzymes, required for transcription factors, antioxidant function, immune system, respiration and neurological function, and is crucial for normal growth and maturation.

Clinical Indications

Suspected deficiency: symptoms include mouth ulcers, a characteristic rash, alopecia, abdominal pain and diarrhoea, with depression and lethargy; classically seen in a high phytate diet.

There is increased risk of zinc deficiency in elderly, alcoholic, critically ill patients, burns, excessive/prolonged gastrointestinal losses and high phytate diets.

Rare inborn errors e.g. acrodermatitis entropathica

Monitoring of nutritional requirements for patients receiving parenteral nutrition or after bariatric surgery

Reference Range

Female

0 – 6 months 5.0 – 21.5 µmol/L
6 months – 19 years 9.8 – 19.0 µmol/L
19 – 65 years 9.6 – 20.5 µmol/L
> 65 years 9.2 – 19.2 µmol/L

Male

0 – 6 months 5.0 – 21.5 µmol/L
6 months – 19 years 9.8 – 19.0 µmol/L
19 – 65 years 10.1 – 20.2 µmol/L
> 65 years 8.0 – 20.0 µmol/L

 

Urine

<1.1 µmol/mmol creatinine
<3.0 – 19.3 µmol/24hr

Sample volume
0.5 mL
Turnaround time
1 week
Sample & Container Required
Serum: Trace element free (royal blue top). Standard blood tubes are often contaminated with zinc and are not acceptable. Urine: Sterile universal 24 hour collection
Transport Storage
Stable at 2-8oC. Sample can be sent by first class post.
Notes

Haemolysed samples are unsuitable for this assay.

Record last updated
September 5, 2025

Sample Container

6ml Trace Metal Silica (Navy blue top with red band on label)

Sample Container

24hr Urine Bottle (Plain label)

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Test Results

Yes, we have a Pathology User Guide

Yes. Please email your request to Imperial.nwlpcustomerservice@nhs.net

Results are communicated to clinical staff and are normally not communicated direct to patients either on telephone requests or in written report. If you need to contact us please click here to view the contact details page

Please contact the Customer Service Team Monday to Friday from 8:30am – 6:00pm on 0203 313 5353. Alternatively, see the Pathology User Guide for how to contact the relevant department. If advice is not urgent you can also email your query to Imperial.nwlpcustomerservice@nhs.net

Additional tests may be added by discussion with the relevant laboratory. The time limit for adding additional tests to a sample already received in the laboratory will depend on the type of sample and the department it was sent to.

Information on the repertoire of tests performed by pathology, including reference ranges, turnaround times and specimen requirements, can be found in the test directory.

NWLP operates UKAS accredited medical laboratories as per the references below. The current scope of accreditation for all NWLP’s laboratories can be found on the UKAS website.

See the following UKAS ref numbers:

  • Clinical Biochemistry Ref: 8673
  • Haematology and Blood Transfusion Ref: 8674
  • Infection & Immunity Sciences (Including Immunology, Virology, Microbiology and Histocompatibility and Immunogenetics ) Ref: 8659
  • Cellular Pathology (Including Histopathology, Cytology and Molecular Pathology) Ref: 9615

If you require copies of our certificate of accreditation and associated documentation please contact Imperial.nwlpcustomerservice@nhs.net.

UKAS requires the laboratories to be accredited for a particular repertoire/scope (ISO15189), any changes or additions to repertoire require assessment by UKAS (extension to scope).

The BD Hospital Tube GuideBD GP Tube Guide and BD Paediatric Tube Guide provide visual references to the correct tube types and collection instructions.

Home testing

INSTRUCTION SHEET FOR BLOOD SAMPLE COLLECTION 

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VIDEO ON BLOOD SAMPLE COLLECTION (without subtitles)

VIDEO ON BLOOD SAMPLE COLLECTION (with subtitles)

Our accreditations

Upholding excellence in diagnostic standards

Our laboratories are accredited by the UK Accreditation Service (UKAS) against the international standard ISO15189:2022. UKAS is the accreditation body for the UK that assesses medical laboratories.

Find out more about our accreditations on the UKAS website.

UKAS website
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