Anti-Phospholipase A2 Receptor Antibody (anit-PLA2R)
The anti-PLA2R (IgG) antibody assay is a quantitative enzyme immunoassay (ELISA) for the in vitro measurement of IgG antibodies targeted against the M-type-phospholipase A2 receptor (PLA2R) on renal podocytes in patient sera.
The anti-PLA2R test is useful in the diagnosis and monitoring of primary membranous glomerulonephritis
Anti-PLA2R antibodies are positive in 75-80% of cases of primary membranous glomerulonephritis.
There is also evidence that levels of anti-PLA2R autoantibodies correlate well with disease activity and progression
<14 RU/ml (negative)
|Sample & container required||Serum - 5ml Gel SST (RUST TOP)|
|Sample volume||Minimum 1ml Serum|
Samples should be transported at room temperature to the laboratory within 2-3 days from collection
|Transport storage||Room temperature|
|Turnaround time||14 days|
This test is currently unaccredited due to a recent change in platform (manual to automation).