Factor H and factor I
| Category | Immunology |
|---|---|
| Test background |
Membranoproliferative glomerulonephritis type II (MPGNII) is associated with dysregulation of the alternative pathway of complement circulation. Factor H and factor I control the alternative pathway activation, and deficiencies of these may lead to MPGNII. |
| Clinical Indications |
Suspected membranoproliferative glomerulonephritis type II (MPGNII). |
| Reference range | Antigenically present |
| Sample & container required | RST (rust top) |
| Sample volume | 5-10 mL (1 mL serum) |
| Turnaround time | 28 days |