Gastric parietal cell antibodies
| Category | Immunology |
|---|---|
| Test background |
Tested as part of LKS screen. GPC antibodies are seen in association with autoimmune gastritis and pernicious anaemia. All positive samples will be tested for presence of antibodies to intrinsic factor. Suggest also measure vitamin B12 levels. |
| Clinical Indications |
Pernicious anaemia (PA) Atrophic gastritis Present in the early stages of PA, frequently diminishing with disease progression. |
| Reference range | Negative |
| Sample & container required | RST (rust top) |
| Sample volume | 5-10 mL (1 mL serum) |
| Turnaround time | 7 days |
| Notes | From March 2020 this test will be unaccredited |