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M-type-phospholipase A2 receptor (Anti-PLA2R)

Category Immunology
Test background

Anti-PLA2R antibodies is a highly specific antibody that occurs in up to 70%-75% of primary membranous glomerulonephritis (MGN) patients, and will provide an important diagnostic marker which will differentiate primary MGN form secondary MGN. This is important to determine as the therapeutic strategies are different for both diseases.

Clinical Indications
Reference range


Negative (normal) Range <14 RU/ml
Weak Positive Range ≥14 to <20 RU/ml
Positive Range ≥20 RU/ml
Sample & container required RST (rust top)
Sample volume 5 mL Blood
Transport storage It is acceptable for serum samples to be sent by post as autoantibodies are stable for 2-3 days at room temperature.
Turnaround time 14 days