Myeloperoxidase antibodies
Category | Immunology |
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Test background |
p-ANCAs are directed against myeloperoxidase and are generally associated with microscopic polyangiitis (MPA), Churg-Strauss syndrome (CSS). See neutrophil cytoplasmic antibodies (ANCA). |
Clinical Indications |
Skin rashes with or without pain (cutaneous vasculitis) Systemic vasculitis General (protean) symptoms, such as feeling unwell, weight loss, night sweats, joint pains Haematuria/proteinuria (kidney-associated) Haemoptysis, difficulty in breathing (lungs) Muscle weakness/numbness of extremities (microvascular) Abdominal pain (gut) In addition to acute heart and brain symptoms when these organs are implicated |
Reference range | <3.5 IU/mL = Neg |
Sample & container required | RST (rust top) |
Sample volume | 5-10 mL (1 mL serum) |
Turnaround time | 5 days |