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Protein (CSF)

Category Biochemistry
Test background

Measurement of CSF protein is used to distinguish septic from aseptic meningitis and is also associated with increased permeability of the blood:brain barrier, vasogenic brain oedema, hypercellularity and release of brain-specific proteins during cell death.

Clinicial Indications

Protein concentrations >1 g/L are often viewed as diagnostic for bacterial, fungal or tuberculous meningitis.

Reference range
0-30 days 0.26-1.35 g/L
1-3 months 0.10-0.86 g/L
3-6 months 0.10-0.54 g/L
6months – 16 yrs 0.10-0.44 g/L
>16 years 0.15-0.45 g/L
Sample & container required CSF in universal container
Sample volume 0.5 mL
Turnaround time 1 day