A2 subtyping
| Category | Blood Transfusion |
|---|---|
| Test background |
It is common practice in many transplant centres to confirm the ABO subtype donors as A1, A1B, A2 or A2B, prior to solid organ transplant. This is to prevent isoagglutinins that can react with the blood group antigens on the cells of the organ being transplanted. |
| Clinical Indications |
Used in transplantation to detect minor subgroups of the A red cell antigen. |
| Reference range | Please contact the laboratory. |
| Sample & container required | EDTA (lavender top) |
| Sample volume | 4 mL for paediatrics; 6 mL for adults |
| Turnaround time | Dependent on clinical requirement. Contact the laboratory to discuss further. |
| Notes | May be referred to the NHS Blood and Transplant service for confirmation if necessary. |