Apolipoprotein A1 (Apo A1)
|Category||Biochemistry >> Proteins|
Apo A1 constitutes the major component of high density lipoprotein (HDL). Apo A1 is an activator of the enzyme lecithin:cholesterol acyltransferase and removes free cholesterol from extrahepatic tissues. Apo A1 concentrations correlate with high density lipoprotein cholesterol and thus low levels are a risk factor for coronary artery disease. Rarely, very low levels are seen in hereditary deficiency of LPA1.
Patients with a personal or family history of high concentrations of lipids and/or premature coronary heart disease Determine cause of high lipid concentrations with suspicion of a deficiency Used with Apo B to check ratio for coronary heart disease risk To monitor effectiveness of changes to lipid-lowering treatment or lifestyle changes
|Sample & container required||SST (gold top) or serum (red top)|
|Sample volume||0.5 mL|
|Transport storage||Stable at 2-8°C for 72 hours. Please freeze pending dispatch for analysis
Sample can be sent by first class post.
|Turnaround time||1 week|
Grossly haemolysed samples are unsuitable for this assay.