Beta-2 Transferrin (Asialo Transferrin, CDT Determination of CSF in Fluid)
| Category | Biochemistry >> Proteins |
|---|---|
| Test background |
An asialo form of transferrin is produced in the cerebral parenchyma by lysosomal hydrolysis of the plasma derived protein from a sialic acid residue. Up to 30% of transferrin in lumbar CSF is in this asialo form. |
| Clinical Indications |
?CSF or Fluid. If a fluid sample is suspected of being CSF, e.g. in possible CSF rhinorrhea, confirmation can be obtained by demonstrating the presence of the asialo band by electrophoresis and immunofixation. This specific test is NOT a suitable for detection of chronic alcohol consumption/cessation of alcohol use. |
| Reference range | N/A |
| Sample & container required | Fresh fluid sample with an accompanying serum sample |
| Sample volume | 50µl Fluid |
| Transport storage | Send to lab immediately. |
| Turnaround time | 1 Week (Samples are run as soon as possible on receipt to the Protein Lab; usually the same or next working day) |