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Beta-2 Transferrin (Asialo Transferrin, CDT)

Category Biochemistry >> Proteins
Test background

An asialo form of transferrin is produced in the cerebral parenchyma by lysosomal hydrolysis of the plasma derived protein from a sialic acid residue. Up to 30% of transferrin in lumbar CSF is in this asialo form.

Clinicial Indications

?CSF or Fluid.

If a fluid sample is suspected of being CSF, e.g. in possible CSF rhinorrhea, confirmation can be obtained by demonstrating the presence of the asialo band by electrophoresis and immunofixation.

Reference range

N/A

Sample & container required Fresh fluid sample with an accompanying serum sample
Sample volume 50µl Fluid
Transport storage Send to lab immediately.
Turnaround time 1 Week
(Samples are run as soon as possible on receipt to the Protein Lab; usually the same or next working day)