Beta-2 Transferrin (Asialo Transferrin, CDT)
|Biochemistry >> Proteins
An asialo form of transferrin is produced in the cerebral parenchyma by lysosomal hydrolysis of the plasma derived protein from a sialic acid residue. Up to 30% of transferrin in lumbar CSF is in this asialo form.
?CSF or Fluid.
If a fluid sample is suspected of being CSF, e.g. in possible CSF rhinorrhea, confirmation can be obtained by demonstrating the presence of the asialo band by electrophoresis and immunofixation.
|Sample & container required
|Fresh fluid sample with an accompanying serum sample
|Send to lab immediately.
(Samples are run as soon as possible on receipt to the Protein Lab; usually the same or next working day)