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Complement C3 nephritic factor

Category Immunology
Test background

A proportion of patients with membranoproliferative glomerulonephritis (types 1, 2 and 3) have C3NF, but it is also found in some patients with partial lipodystrophy or acute post-streptococcal glomerulonephritis.

Clinicial Indications

Mesangiocapillary glomerulonephritis.
Only performed if C3 is low.

Reference range

Negative

Sample & container required RST (rust top) Separate and freeze immediately Transport frozen
Sample volume 5-10 mL (1 mL serum)
Turnaround time 28 days