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Dehydroepiandrosterone sulphate (DHEAS)

Category Biochemistry >> Endocrinology
Test background

DHEAS is derived from the adrenal glands. Blood measurements of DHEAS are useful to detect excess adrenal activity as seen in DHEA-secreting adrenal tumours or incidences of hyperplasia including certain forms of CAH. Women with PCOS tend to have normal or mildly elevated levels of DHEAS.

Clinical Indications

DHEAS assay is indicated for the differential diagnosis of PCOS and CAH Presentation of unexplained hirsuitism Presentation of adrenal mass, ie. suspected adrenal tumour

Reference range
11 Years 0 – 5 μmol/L
11-19 years 0 – 12 μmol/L
20-40 years 0.7-11.5 μmol/L
40-60 years 0.8-6.9 μmol/L
60 years 0.4-4.7 μmol/L
Sample & container required Serum (red top)
Sample volume 0.5 mL
Transport storage Stable at 2-8°C for 24 hours. Please freeze pending dispatch for analysis. Send to lab frozen.
Turnaround time 1 week

Grossly haemolysed samples are unsuitable for this assay.