Factor V Leiden
|Category||Specialist Integrated Haematological Malignancy Diagnostic Service (SIHMDS) >> Molecular Pathology|
Factor V Leiden mutation causes hypercoagulability disorders. The blood develops a tendency to form abnormal blood clots that can block blood vessels. Patients with Factor V Leiden thrombophilia have a higher than average risk of developing DVT. The probability of developing a clot in a blood vessel depends on whether the patient inherits one or two copies of the Factor V Leiden mutation.
A significant proportion of patients who present with DVT or pulmonary embolisms have a Factor V Leiden mutation. It would be prudent to eliminate Factor V Leiden mutation as being the cause for any thrombotic event in any Caucasian patient below the age of 45, or in any person with a family history of venous thrombosis.
|Sample & container required||EDTA (lavender top)|
|Sample volume||>1ml Please note, if the blood counts are abnormal (high or low white cell count), the volumes of blood should be adjusted accordingly.|
|Turnaround time||10 working days|