Ganglioside antibodies
| Category | Immunology |
|---|---|
| Test background |
There is a wide range of ganglioside antibodies, which includes IgG and IgM antibodies to GM1, GM2, GD1A, GD1B and GQ1b. GM1 antibodies are seen in Guillain-Barré syndrome. GQ1b antibodies are seen in the Miller Fisher variant. |
| Clinical Indications |
Suspected Guillain-Barré syndrome |
| Reference range | <500 = negative |
| Sample & container required | RST (rust top), Can also be performed on CSF |
| Sample volume | 5-10 mL (1 mL serum) |
| Turnaround time | 28 days |
| Notes | Not currently performed in house; this test is referred to Institute of Neurology, Queens Square. |