Ganglioside antibodies
Category | Immunology |
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Test background |
There is a wide range of ganglioside antibodies, which includes IgG and IgM antibodies to GM1, GM2, GD1A, GD1B and GQ1b. GM1 antibodies are seen in Guillain-Barré syndrome. GQ1b antibodies are seen in the Miller Fisher variant. |
Clinical Indications |
Suspected Guillain-Barré syndrome |
Reference range | <500 = negative |
Sample & container required | RST (rust top), Can also be performed on CSF |
Sample volume | 5-10 mL (1 mL serum) |
Turnaround time | 28 days |
Notes | Not currently performed in house; this test is referred to Institute of Neurology, Queens Square. |