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0203 313 5353

Ganglioside antibodies

Category Immunology
Test background

There is a wide range of ganglioside antibodies, which includes IgG and IgM antibodies to GM1, GM2, GD1A, GD1B and GQ1b. GM1 antibodies are seen in Guillain-Barré syndrome. GQ1b antibodies are seen in the Miller Fisher variant.

Clinicial Indications

Suspected Guillain-Barré syndrome
Chronic demyelinating polyneuropathy
Multifocal motor neuropathy

Reference range

<500 = negative

Sample & container required RST (rust top), Can also be performed on CSF
Sample volume 5-10 mL (1 mL serum)
Turnaround time 28 days

Not currently performed in house; this test is referred to Institute of Neurology, Queens Square.