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Results Line and Enquiries

0203 313 5353

HIV-1 Resistance (Protease and reverse transcriptase)

Category Virology
Test background

Decreased susceptibility of HIV-1 to antiretroviral drugs is usually associated with sequence changes in the viral genome (genotypic drug resistance). Detection of these mutations in the viral genome can be used to predict accurately the susceptibility of the virus to all currently licensed antiretroviral drugs and thus can be used to optimise the use of antiretroviral treatment on an individual patient basis. The routine test for resistance to protease and reverse-transcriptase inhibitors generates a sequence covering the resistance associate sites in the protease and the reverse-transcriptase gene.

Clinical Indications

Baseline and/or when failing therapy

Reference range

Please contact the laboratory.

Sample & container required Plasma or Serum
Sample volume 1mL
Turnaround time 14 days

Must have quantifiable HIV-1 viral load.

This assay has changed to the Vela NGS assay is currently awaiting UKAS accreditation.