HLA-B*27 Typing (B27)
| Category | Immunology |
|---|---|
| Test background | |
| Clinical Indications |
Although HLA B27 is present in approximately 10% of the normal population, it if found in 88-96% of patients with ankylosing spondylitis (AS). It is also associated with other rheumatological disorders, including Reiter's syndrome and is a strong diagnostic indicator for AS. A positive result indicates the presence of this antigen. |
| Reference range | Negative |
| Sample & container required | 5-10 mL Whole Blood - EDTA ( 6 ml pink top) |
| Sample volume | 5 mls |
| Turnaround time | 14 days |
| Notes | Samples must be sent via first class post or courier The laboratory is accredited for this test by the European Federation of Immunogenetics (EFI) however due to a change in platform it is currently awaiting UKAS accreditation under extension to scope. |