HLA-B*27 Typing (B27)
| Category | Immunology >> Histocompatibility and Immunogenetics |
|---|---|
| Clinical Indications |
Although HLA B27 is present in approximately 10% of the normal population, it if found in 88-96% of patients with ankylosing spondylitis (AS). It is also associated with other rheumatological disorders, including Reiter's syndrome and is a strong diagnostic indicator for AS. A positive result indicates the presence of this antigen. |
| Reference range | Negative |
| Sample & container required | 4mL Whole Blood – EDTA (lavender top) |
| Sample volume | 4 mL |
| Turnaround time | 14 days |
| Notes | Samples must be sent via first class post or courier The laboratory is accredited for this test by the European Federation of Immunogenetics (EFI) and UKAS for HLA typing using EDTA samples.
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