Skip to main content

Login to North West London Pathology – consumables service

If you need a new account or you have a query about your order, please telephone the pathology call centre on 0203 313 5353.

If you have forgotten your password you can reset this yourself. Please click here if you have forgotten your password.

Results Line and Enquiries

0203 313 5353

HLA-B*57:01 (B57)

Category Immunology >> Histocompatibility and Immunogenetics
Test background

Most patients can safely take abacavir; however, a small number of patients experience a severe side effect known as abacavir hypersensitivity. The most common symptoms are skin rash, fever, nausea, vomiting and diarrhea. About 5% of patients who take abacavir experience abacavir hypersensitivity. This reaction can sometimes be very serious and in some cases can cause death. Patients who are HLA-B*57:01 are much more likely to have this reaction than patients who do not. Therefore, patients with the HLA-B*57:01 gene should not take abacavir. Approximately 5-8% of Europeans, 1-2% of Asians, and 2% of Africans have this gene.

Clinical Indications

Screening for Abacavir Hypersensitivity

Reference range


Sample & container required 4mL Whole Blood - EDTA
Sample volume 4 mL
Transport storage Samples must be sent via first class post or courier
Turnaround time 14 days

Samples must be sent via first class post or courier

The laboratory is accredited for this test by the European Federation of Immunogenetics (EFI) and UKAS for HLA typing using EDTA samples.