Inhibitor screen
| Category | Haematology Haematology >> Specialised Coagulation Services |
|---|---|
| Test background |
The Inhibitor Screen is used to identify the presence of immediate or time-dependent inhibitors to coagulation factors. Inhibitors may be naturally acquired in certain disease states or may develop in response to factor concentrate treatment regimens in haemophiliacs. Inhibitors may be suspected when in vivo recovery is significantly lower than expected given the dose of factor concentrate administered. |
| Clinical Indications |
Inhibitor screen: Suspicion of acquired haemophilia or following loss of efficacy post-treatment with factor concentrates. |
| Reference range | For advice with interpretation please contact the lab (x32449) or haematology clinical team. |
| Sample & container required | 2.7 mL sodium citrate (pale blue top) adults; 1.8 mL sodium citrate (pale blue top) paediatrics |
| Turnaround time | 14 days |
| Notes | Samples will be rejected if under/over-filled, clotted or haemolysed. The laboratory is not UKAS accredited for this test due to a change in equipment/assay. Awaiting assessment. |