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Intrinsic factor antibodies

Category Immunology
Test background

Antibodies against intrinsic factor are present in 50-60 % of patients with pernicious anaemia. Their presence may pre-date the development of B12 deficiency. It is recommended to also check vitamin B12 levels.

Clinical Indications

Differential diagnosis of pernicious anaemia (autoimmune causes are not refractory to dietary B12 supplementation).

Reference range


Sample & container required RST (rust top)
Sample volume 5-10 mL (1 mL serum)
Turnaround time 14 days

Due to a change in platform, the laboratory is not currently accredited for this test.