Intrinsic factor antibodies
| Category | Immunology |
|---|---|
| Test background |
Antibodies against intrinsic factor are present in 50-60 % of patients with pernicious anaemia. Their presence may pre-date the development of B12 deficiency. This test is performed by ELISA. |
| Clinical Indications |
Differential diagnosis of vitamin B12 deficiency. |
| Reference range | Negative |
| Sample & container required | Serum (RST rust top) |
| Sample volume | 5-10 mL blood (1 mL serum) |
| Turnaround time | 14 days |