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Iron (urine)

Category Biochemistry >> Trace elements
Test background

Iron is routinely measured in serum/plasma to assess iron stores and is rarely measured in urine. However, urine iron measurements can be used to monitor chelation therapy of patients with iron overload. In these cases the chelating agents interfere in dye-binding assays, so routine automated chemistry tests cannot be used. This method uses ICP-MS, which does not suffer from chelating agent interference.

Clinical Indications

Measurement of urinary iron excretion during chelation therapy

Reference range

<1.0 µmol/L
<1.0 µmol/24hrs
<0.05 µmol/mmol creatinine

Sample & container required Random urine or 24 hour urine collection
Sample volume 0.5 mL
Transport storage Stable at 2-8°C Sample can be sent by first class post.
Turnaround time 1 week

Increased concentrations can be seen in proteinuria.