Islet cell antibodies
| Category | Immunology |
|---|---|
| Test background |
Testing for Islet cell antibodies by IIF is no longer recommended by NICE (NG17), please request GAD65 and IA2 antibody for T1DM screening. |
| Clinical Indications |
Differential diagnosis of type II diabetes mellitus and LADA (latent autoimmune diabetes in adults) Screening of first degree relatives for risk of developing insulin dependent DM (IDDM) May also be used to determine the risk of IDDM in gestational diabetes |
| Reference range | Negative |
| Sample & container required | RST (rust top) |
| Sample volume | 5-10 mL (1 mL serum) |
| Turnaround time | 14 days |
| Notes | This test is currently unaccredited due to a recent change in platform/assay. |