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Low density lipoprotein cholesterol (LDL)

Category Biochemistry
Test background

The fasting lipid profile assesses total cholesterol, total triglycerides and high density lipoprotein cholesterol. From these, low density lipoprotein cholesterol is calculated.

Clinical Indications

Family history of cardiovascular or other thrombotic events Diagnosis and monitoring of hyperlipidaemia Monitoring of high-risk groups, eg. hypertensive, obese, diabetics, etc.

Reference range

<3.0 mmol/L

Sample & container required SST (gold top)
Sample volume 0.5 mL
Turnaround time 1 day

Non-HDL cholesterol (total chol minus HDL chol) is recommended for CVD risk prediction; fasting samples are not required for this.

Non-HDL cholesterol targets for patients treated for CVD risk reduction are 40 % reduction from baseline (NICE CG181, 2014) or <2.5 mmol/L (JBS3. Heart 2014;100:ii1)

The JBS3 CVD risk estimator is at