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MAG (Myelin Associated Glycoprotein antibodies)

Category Immunology
Test background

Myelin-associated glycoprotein (MAG) autoantibodies are seen in some patients with peripheral neuropathy and frequently occur with IgM paraproteinaemia (Waldenstrom’s macroglobulinaemia, monoclonal gammopathy of uncertain significance (MGUS)).

Clinical Indications

Adult onset neuropathy (distal, symmetrical) gait disorder, tremor

Reference range

Negative <1000 BTU (Bulhmann titre units)

Sample & container required RST (rust top)
Sample volume 5-10 mL blood (1 mL serum)
Turnaround time 28 days

Not currently performed in house; this test is performed by ELISA at OUH, Oxford Immunology Laboratory