MAG (Myelin Associated Glycoprotein antibodies)
| Category | Immunology |
|---|---|
| Test background |
Myelin-associated glycoprotein (MAG) autoantibodies are seen in some patients with peripheral neuropathy and frequently occur with IgM paraproteinaemia (Waldenstrom’s macroglobulinaemia, monoclonal gammopathy of uncertain significance (MGUS)). |
| Clinical Indications |
Adult onset neuropathy (distal, symmetrical) gait disorder, tremor |
| Reference range | Negative <1000 BTU (Bulhmann titre units) |
| Sample & container required | RST (rust top) |
| Sample volume | 5-10 mL blood (1 mL serum) |
| Turnaround time | 28 days |
| Notes | Not currently performed in house; this test is performed by ELISA at OUH, Oxford Immunology Laboratory |