Anti-mitochondrial antibodies (AMA), which are directed against components of mitochondrial dehydrogenase complexes, are detected by indirect immunofluorescence using mouse liver/kidney/stomach (LKS) substrate. Positive results are then tested by liver immunoblot for confirmation.
Mitochondrial antibodies are associated with primary biliary cirrhosis AMA are also detected in patients with chronic hepatitis C infection and systemic sclerosis
|Sample & container required||RST (rust top)|
|Sample volume||5-10 mL (1 mL serum)|
|Turnaround time||7 days|
This test is currently unaccredited due to a recent change in platform.