Myeloid Panel (next generation sequencing)
| Category | Specialist Integrated Haematological Malignancy Diagnostic Service (SIHMDS) >> Molecular Pathology |
|---|---|
| Test background |
An NGS panel used for the investigation of myeloid malignancies such as AML and MDS. This assay covers the following: Hotspot genes - ABL1, BRAF, CBL, CSF3R, DNMT3A, FLT3, GATA2, HRAS, IDH1, IDH2, JAK2, KIT, KRAS, MPL, MYD88, NPM1, NRAS, PTPN11, SETBP1, SF3B1, SRSF2, U2AF1, WT1 Full genes - ASXL1, BCOR, CALR, CEBPA, ETV6, EZH2, IKZF1, NF1, PHF6, PRPF8, RB1, RUNX1, SH2B3, STAG2, TET2, TP53, ZRSR2 |
| Clinical Indications |
For diagnostic, prognostic and predictive testing in myeloid malignancies such as AML and MDS. |
| Sample & container required | 4ml Blood or >1ml bone marrow in EDTA (lavender/purple top) |
| Turnaround time | 21 calendar days |