Neuromyelitis optica/NMO (Aquaporin 4) Antibody
| Category | Immunology |
|---|---|
| Test background |
Aquaporin 4 antibodies are found in >80% of patients with neuromyelitis optica (NMO) and 50% of patients with longitudinally extensive transverse myelitis. NMO antibodies are not usually found in optic neuritis without spinal cord involvement. |
| Clinical Indications |
NMO, myelitis |
| Reference range | Negative |
| Sample & container required | Serum (rust top RST tube) |
| Sample volume | 5-10 mL blood (1 mL serum) |
| Turnaround time | 28 days |
| Notes | Referral Test, not performed in house. Referral Laboratory: Neuroimmunology Laboratory, Queens Square, UCLH , London. |