Elastase is unaffected by intestinal passage, so faecal concentrations (which are 5-fold greater than in pancreatic juice) more accurately reflect the amount of enzyme secreted from the pancreas and consequently serve as a means of assessing pancreatic function.
Investigation of malabsorption due to exocrine pancreatic insufficiency.
|Sample & container required||Faecal sample in universal container|
|Sample volume||5 g|
|Turnaround time||Up to 6 weeks|
Not currently performed in house; this is a referred test. Can get transient low values during enteric viral infection, suggest repeat in 2 weeks.