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Category Biochemistry
Test background

Phenobarbitone is a general central nervous system suppressant that has proven effective in the control of generalised and partial seizures. It is frequently co-administered with phenytoin for control of complex seizure disorders, and with valproic acid for complex partial seizures.

Clinical Indications

Therapeutic drug monitoring Assessing compliance or toxicity (symptoms of overdosage include: ataxia, nystagmus, fatigue or attention loss, progressing to respiratory arrest when pulmonary support is not supplied manually)

Reference range

10-40 mg/L

Sample & container required SST (gold top)
Sample volume 0.5 mL
Turnaround time 1 day