Phenobarbitone
| Category | Biochemistry |
|---|---|
| Test background |
Phenobarbitone is a general central nervous system suppressant that has proven effective in the control of generalised and partial seizures. It is frequently co-administered with phenytoin for control of complex seizure disorders, and with valproic acid for complex partial seizures. |
| Clinical Indications |
Therapeutic drug monitoring Assessing compliance or toxicity (symptoms of overdosage include: ataxia, nystagmus, fatigue or attention loss, progressing to respiratory arrest when pulmonary support is not supplied manually) |
| Reference range | 10-40 mg/L |
| Sample & container required | SST (gold top) |
| Sample volume | 0.5 mL |
| Turnaround time | 1 day |