PLA2R antibodies (Anti-Phospholipase A2 Receptor Antibody)
| Category | Immunology |
|---|---|
| Test background |
The anti-PLA2R (IgG) antibody assay is a quantitative enzyme immunoassay (ELISA) for the in vitro measurement of IgG antibodies targeted against the M-type-phospholipase A2 receptor (PLA2R) on renal podocytes in patient sera. Anti-PLA2R antibodies are positive in 75-80% of cases of primary membranous glomerulonephritis and correlate well with disease activity and progression. This test is performed by ELISA. |
| Clinical Indications |
The diagnosis and monitoring of primary membranous glomerulonephritis |
| Reference range | <14 RU/ml |
| Sample & container required | Serum (rust top RST tube) |
| Sample volume | 5-10 mL blood (1mL serum) |
| Turnaround time | 14 days |