Pneumococcal serotypes
| Category | Immunology |
|---|---|
| Test background |
This test measures the antibody level of each of the 23 capsular serotypes of Streptococcus pneumonia and is used to assess vaccine response in patients with suspected immune deficiency and in the assessment of patients with specific polysaccharide antibody deficiency. This assay identifies response to serotypes only covered by the polysaccharide (T cell independent) vaccine (serotypes 8, 9N, 12F, 15B) alongside those serotypes found in the protein conjugate vaccine (serotypes 1, 3, 4, 6B, 9V, 14, 18c, 19A, 23F). |
| Clinical Indications |
Investigation of primary and secondary immunodeficiency |
| Reference range | The putative level of protection for each serotype is ≥0.35 µg/ml Ranges verified by referral laboratory |
| Sample & container required | Serum (RST rust top) |
| Sample volume | 5-10 mL blood (1 mL serum) |
| Turnaround time | 28 days |