Prednisolone is a commonly prescribed glucocorticoid. High doses are used in conditions such as Rheumatoid Arthritis and Polymyalgia Rheumatica for its anti-inflammatory actions. Low doses are used in conditions such as adrenal insufficiency and CAH for its corticosteroid replacement properties. Serum prednisolone concentrations can be used to assess whether a dosing regimen provides suitable steroid replacement.
-To assess whether adequate steroid replacement is achieved on a prednisolone dosing regimen. A single prednisolone level should be taken 8 hours after the replacement dose is administered.
An 8 hour post dose level: 15-25 µg/L indicates adequate steroid replacement
|Sample & container required
|Serum SST (gold top) or serum (red top)