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Protein electrophoresis (paraprotein screen)

Category Biochemistry >> Proteins
Test background

Electrophoresis of serum proteins facilitates screening and diagnosis of haematological malignancy. Serum protein electrophoresis may also have some value in monitoring of inflammatory responses, assessment of nutritional status and detection of specific protein abnormalities such as A1AT deficiency.

Clinical Indications

Hyperglobulinaemia/Hypoglobulinaemia Screening for haematological malignancy Monitoring of established plasma cell dyscrasia

Reference range

See report

Sample & container required SST (gold top) or serum (red top)
Sample volume 0.5 mL
Transport storage Stable at 2-8°C for 72 hours. Please freeze pending dispatch for analysis. Sample can be sent by first class post.
Turnaround time 1 week (please allow up to 2 weeks if further analysis is required)

Where appropriate, further analysis will be carried out, eg. immunofixation/immunotyping and quantitation of paraproteins.
Grossly haemolysed samples are unsuitable for this assay.