Quantification (or titration) of red cell alloantibodies
Clinically significant maternal antibodies detected during initial antenatal group and antibody screening require referral to assist in the monitoring of antibody levels during the pregnancy.
Red cell antibodies of potential clinical significance in pregnancy can be monitored to see how strong they are and whether there is any change during the course of the pregnancy.
Negative (ie. no circulating antibodies)
Generally, the significance of anti-D and anti-c levels during pregnancy is as follows:
• anti-D less than 4 IU/mL: HDN unlikely;
|Sample & container required||EDTA (lavender top)|
|Sample volume||4 mL for paediatrics; 6 mL for adults|
|Turnaround time||7-14 days, dependent on clinical requirement. Contact the laboratory to discuss further.|
This test may be referred to a reference laboratory for additional testing.