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Category Biochemistry >> Endocrinology
Test background

The S-100 protein family of acidic calcium binding proteins consists of 17 monomers, each of which exhibits a unique pattern of tissue-specific expression. Two of the monomeric proteins, S-100A1 and S-100B, are found in high concentrations in the nervous system of vertebrates. These two monomers form either homo- or hetero-dimers; S-100B is present in high concentrations in glial and Schwann cells. Several studies have demonstrated the value of S-100 in the management of patients with malignant melanoma.

Clinical Indications

Management of patients with malignant melanoma.

Reference range

<0.15 µg/L

Sample & container required Serum (Red top or SST (gold top)
Sample volume 0.5 mL
Transport storage Stable at 2-8°C for 24 hours. Please freeze pending dispatch for analysis. Send to lab frozen.
Turnaround time 10 days

Grossly haemolysed samples are unsuitable for this assay.