S-100
| Category | Biochemistry >> Endocrinology |
|---|---|
| Test background |
The S-100 protein family of acidic calcium binding proteins consists of 17 monomers, each of which exhibits a unique pattern of tissue-specific expression. Two of the monomeric proteins, S-100A1 and S-100B, are found in high concentrations in the nervous system of vertebrates. These two monomers form either homo- or hetero-dimers; S-100B is present in high concentrations in glial and Schwann cells. Several studies have demonstrated the value of S-100 in the management of patients with malignant melanoma. |
| Clinical Indications |
Management of patients with malignant melanoma. |
| Reference range | <0.15 µg/L |
| Sample & container required | Serum (Red top or SST (gold top) |
| Sample volume | 0.5 mL |
| Transport storage | Stable at 2-8°C for 24 hours. Please freeze pending dispatch for analysis. Send to lab frozen. |
| Turnaround time | 10 days |
| Notes | Grossly haemolysed samples are unsuitable for this assay. |