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Salivary duct antibodies

Category Immunology
Test background

Antibodies to the epithelial cells of the salivary duct occur in around 50% of patients with Sjögren’s syndrome (SjS).

Please note the presence of Ro/SSA antibody (see ENA profile) is a more sensitive marker of SjS and forms part of the 2016 ACR/EULAR classification criteria.

Clinical Indications

Suspected Sjögren’s syndrome

Reference range


Sample & container required Serum (RST rust top)
Sample volume 5-10 mL blood (1 mL serum)
Turnaround time 28 days

Not currently performed in house; this test is referred to the Protein Reference Unit (PRU), Sheffield.