Salivary duct antibodies
| Category | Immunology |
|---|---|
| Test background |
Antibodies to the epithelial cells of the salivary duct occur in around 50% of patients with Sjögren’s syndrome (SjS). Please note the presence of Ro/SSA antibody (see ENA profile) is a more sensitive marker of SjS and forms part of the 2016 ACR/EULAR classification criteria. |
| Clinical Indications |
Suspected Sjögren’s syndrome |
| Reference range | Negative |
| Sample & container required | Serum (RST rust top) |
| Sample volume | 5-10 mL blood (1 mL serum) |
| Turnaround time | 28 days |
| Notes | Not currently performed in house; this test is referred to the Protein Reference Unit (PRU), Sheffield. |