Serological investigation of autoimmune haemolytic anaemia
| Category | Blood Transfusion |
|---|---|
| Test background |
Autoimmune haemolytic anaemia (AIHA) is caused by autoantibody-induced haemolysis (the premature destruction of circulating red blood cells). Usually idiopathic, it is also associated with infection, lymphoproliferative disorders, autoimmune diseases, and some drugs. |
| Clinical Indications |
Tests to determine the presence and specificity of a red cell autoantibody if AIHA is suspected. |
| Reference range | Negative (ie. no evidence of autoimmune haemolytic anaemia). |
| Sample & container required | EDTA (lavender top) |
| Sample volume | 2 x 6 mL |
| Turnaround time | Dependent on clinical requirement. Contact the laboratory to discuss further. |
| Notes | If autoimmune haemolytic anaemia is suspected, discuss with a haematologist and/or the Blood Transfusion department to guide investigation. |