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Sugar Chromatography (Urine)

Category Biochemistry >> Metabolic
Test background

This test is performed following a positive screen for Urine Reducing Substances in order to identify the specific sugars present, and provide a qualitative estimation. Sugar chromatography may aid the diagnosis of classical galactosaemia, sucrose malabsorption, lactose intolerance or fructosuria/hereditary fructose intolerance.

Glucose is commonly present in small amounts in the urine of healthy individuals. Lactose, and galactose, may also be present following the ingestion of milk and milk products.

Other sugars of dietary origin (eg. arabinose, xylose, fructose) may also be present as trace amounts, or as a result of the rare disorder of essential pentosurias.

Clinical Indications

Neonatal/infantile presentation of generalised failure to thrive symptomology, chronic diarrhoea, hepatic dysfunction.

Reference range

See report

Sample & container required Random urine in universal container
Sample volume 5ml
Transport storage Transport samples to laboratory immediately. Samples from outside NWLP should be sent frozen.
Turnaround time 3-4 weeks

For investigation of classical galactosaemia, infant must be on lactose-containing milk feeds at time of urine collection.