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Tetanus antibodies

Category Immunology
Test background

Tetanus antibodies are measured as part of an immune deficiency screen for patients with opportunistic or recurrent infections. They have no value in tetanus disease diagnosis. Tetanus antibodies are used as a measurement of the T-cell-dependent response to protein. They are recall antigens requiring prior immunisation. Patients under 4 months old or the elderly may have absent or low responses due to insufficient immunisation.

Clinicial Indications

Assessment of an antibody response to tetanus toxoid vaccine Aiding the diagnosis of immunodeficiency (acquired, congenital or iatrogenic, ie. following administration of immunosuppressive agents)

Reference range

Minimum protective level >0.15IU/mL

Sample & container required RST (rust top)
Sample volume 5-10 mL (1 mL serum)
Turnaround time 14 days
Notes

This test is currently unaccredited due to a recent change in platform.