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Category Microbiology
Test background

If prolonged treatment with Tobramycin is anticipated, regular monitoring of pre-dose serum levels will be required.

Clinical Indications

Take a blood sample immediately prior to the 2nd dose (if duration greater than 48 hours). Do not wait for the result – give second dose as planned. If the level comes back ≥1mg/L the 3rd dose should be adjusted.

Reference range

Pre-dose (trough) <1mg/l

Sample & container required Serum SST rust top
Sample volume 0.5ml
Turnaround time 2-3 Days

Tobramycin assays are now referred externally to Bristol Antimicrobial Reference laboratory. Sample referral and reporting of results is managed by the Infection and Immunity laboratory.