If prolonged treatment with Tobramycin is anticipated, regular monitoring of pre-dose serum levels will be required.
Take a blood sample immediately prior to the 2nd dose (if duration greater than 48 hours). Do not wait for the result – give second dose as planned. If the level comes back ≥1mg/L the 3rd dose should be adjusted.
Pre-dose (trough) <1mg/l
|Sample & container required||Serum SST rust top|
|Turnaround time||2-3 Days|
Tobramycin assays are now referred externally to Bristol Antimicrobial Reference laboratory. Sample referral and reporting of results is managed by the Infection and Immunity laboratory.