Voltage gated calcium antibodies (VGC, calcium channel antibodies)
| Category | Immunology |
|---|---|
| Test background |
Voltage gated calcium channel antibodies are seen in 85% of patients with Lambert-Eaton myasthenic syndrome (LEMS). |
| Clinical Indications |
Suspected Lambert-Eaton myasthenic syndrome |
| Reference range | Negative = <45pM |
| Sample & container required | Serum (RST rust top), CSF not required |
| Sample volume | 5-10 mL blood (2 mL serum); |
| Turnaround time | 28 days |
| Notes | Not currently performed in house; this test is performed by radioimmunoassay at OUH Oxford Immunology Laboratory |