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North West London Pathology > Tests > Whole genome sequencing (haematological malignancies)

Whole genome sequencing (haematological malignancies)

Category Specialist Integrated Haematological Malignancy Diagnostic Service (SIHMDS) >> Molecular Pathology
Test background

For the detection of somatic and germline mutations and potential future biomarkers such as mutational signatures and tumour burden.
Clinical Indications

Current eligibility:
- All patients (adult and paediatric) with acute leukaemia (includes acute myeloid leukaemia, acute lymphoblastic leukaemia and acute leukaemia of ambiguous lineage) at initial diagnosis and/or on relapse.
- Paediatric patients with any other type of haematological malignancy at diagnosis and relapse.
- Proven or Suspected Haematological Tumours Exhausted all Standard of Care Testing and Treatment.

Please liaise with the laboratory before sending samples for testing.
Sample & container required For onward referral to GOSH the following is required:
- Patient choice consent form
- GMS test order form
- Appropriate germline sample
- Tumour sample

For more information please liaise with the laboratory.
Sample container Please liaise with the laboratory before sending samples for testing.
Turnaround time 42 calendar days