The Trace Element laboratory is a member of the Supra-Regional Assay Service. The service may be used by any external hospital, laboratory or other appropriate organisation. The laboratory is recognised by the Employment Medical Advisory Service (EMAS) for occupational lead monitoring.
The laboratory measures an extensive repertoire of trace elements routinely and is able to measure other elements on request. Information and advice (including discussion and interpretation of results) is available during working hours from Nick Martin, Consultant Clinical Scientist, as well as other staff members. The laboratory is involved in a variety of research and development projects, results of which are presented at relevant meetings and subsequently for publication and peer review.
The laboratory has a number of special interests that including:
- The development of fractionated copper assays for the diagnosis of Wilson’s disease
- The measurement of titanium by high resolution magnetic sector-field ICP-MS
- Metal release from surgical implants with a particular interest in titanium
Selected Recent Publications:
- Blood and plasma titanium levels associated with well-functioning hip implants. Swiatkowska I, Martin NG, Henckel J, Apthorp H, Hamshere J, Hart AJ. J Trace Elem Med Biol. 2020; 57:9-17
- Blood titanium level as a biomarker of orthopaedic implant wear. Swiatkowska I, Martin N, Hart AJ. J Trace Elem Med Biol. 2019 May;53:120-128
- Atomic Spectrometry Update: review of advances in the analysis of clinical and biological materials, foods and beverages. Taylor A, Barlow N, Day MP, Hill S, Martin N and Patriarca M. J. Anal. At. Spectrom., 2018,33, 338-382
- Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats. Seiffert J, Buckley A, Leo B, Martin NG, Zhu J, Dai R, Hussain F, Guo C, Warren J, Hodgson A, Gong J, Ryan MP, Zhang JJ, Porter A, Tetley TD, Gow A, Smith R, Chung KF. Respir Res. 2016 Jul 19;17(1):85